TANSHINONE IIA SECRETS

The big GTPase dynamin is essential for clathrin-dependent coated-vesicle formation. Dynasore can be a mobile-permeable small molecule that inhibits the GTPase activity of dynamin1, dynamin2 and Drp1, the mitochondrial dynamin. Dynasore was identified inside of a screen of ~16,000 compounds for inhibitors from the dynamin2 GTPase.That is an open ac